Biophysical Picture in brain
My research areas: epigenetics, subconscious. visual thinking, visual representation, the key role of platelets and intestinal serotonin in health, environmental pollution, among others.
The most important area of my research is biophysical visual virtual reality in the brain:
I deal with the natural biophysical substrate of visual perception and visual imagery. The main goal of my research is to prove that intrinsic pictures can be emerged by redox and biophoton processes in retinotopically organized neurons of visual areas during visual imagery, visual hallucination, and REM dream pictures within the brain.
Kosslyn`s reality simulation principle states that visual mental imagery mimics the corresponding events in the world. However, my concept of intrinsic biophysical visual virtual reality (by bioluminescent photons and iterative processes) in early retinotopic areas may be nothing else than the first possible biophysical basis of the reality simulation principle.
I hope that my researcher of biophysical picture representation can bring a brand new ways in the brain and cellular researchers, visual prosthesis, and artificial intelligence in the future. I can explain numerous brain related phenomena by biophysical picture representation model in a convergent manner (such as: phosphenes, negative afterimages, saccades, blind sight, visual imagery and perception, REM dream pictures, visual hallucination, autism, savant skill, some color illusions, synaesthesia, etc.
I do not claim to solve the secret of consciousness, but propose that the evolution in the higher levels of complexity made possible the emergence of intrinsic picture representation of the external visual world by regulated redox and bioluminescent biophotons in the visual system during visual perception and visual imagery.
Email: bokkoni@yahoo.com
I am looking for sponsors.
Published papers
• Császár N, *Bókkon I. (2023) Hypnotherapy and IBS: Implicit and simple stress memory in ENS? Heliyon, 1, e12751. Open access
• Császár-Nagy N, Bob P, *Bókkon I. A Multidisciplinary Hypothesis about Serotonergic Psychedelics. Is it Possible that a Portion of Brain Serotonin Comes From the Gut? J Integr Neurosci. 2022 Aug 31;21(5):148. https://www.imrpress.com/journal/JIN/21/5/10.31083/j.jin2105148
•Császár N., Scholkmann F., *Bókkon I., (2021) Implications on hypnotherapy: neuroplasticity, epigenetics, and pain. Neuroscience & Biobehavioral Reviews. 131, 755–7
•Császár N, *Bókkon I. (2021) Gut serotonin as a general membrane permeability regulator. Current Neuropharmacology. DOI: 10.2174/1570159X19666210921100542
•*Bókkon I, Kapócs G, Vucskits A, Erdöfi-Szabó A, Vagedes J, Scholkman F., Szőke H. (2021) COVID-19: Implications on platelets, mitochondria, D vitamin, serotonin, and gut microbiota Current Medicinal Chemistry. DOI: 10.2174/0929867328666210526100147
•Tahereh Esmaeilpour, Esmaeil Fereydouni, Farzaneh Dehghani István Bókkon, Mohammad-Reza Panjehshahin, Noemi Császár-Nagy and Vahid Salari.(2020) An Experimental Investigation of Ultraweak Photon Emission from Adult Murine Neural Stem Cells Scientific Reports 10(1):463
•Szőke H., Kovács Z., *Bókkon I., Vagedes J., Erdőfi Szabó A., Hegyi G., Sterner M.-G, Kiss Á., Kapócs G. (2020) GUT DYSBIOSIS AND SEROTONIN: Intestinal 5-HT as a ubiquitous membrane permeability regulator in host tissues, organs and the brain. Reviews in the Neurosciences. 31(4):415-425
•Császár N, Bókkon I. * (2019) Twin Loss in the Uterus: Neurodevelopmental Impairment and Reduced Resilience? Activitas Nervosa Superior 61, 217–226
•Szőke H, et al. Bókkon I.* (2018) Assisted reproductive technology: stress-related epigenetic and neurodevelopmental risk? Activitas Nervosa Superior 60, 95–106.
• Császár N, Kapócs G, Bókkon I. * (2018) Classical hallucinogens: the special role of the visual system. Reviews in the Neurosciences. 30(6):651-669
• Csázár N, Bókkon I.*(2018) Mother-newborn separation at birth in hospitals: A possible risk for neurodevelopmental disorders? Neurosci Biobehav Rev. 84:337-351.
• Csázár N, Kapócs G, Bókkon I.* (2018) A possible key role of vision in the development of schizophrenia. Reviews in the Neurosciences. 30(4):359-379
• Salari, V., Scholkmann, F., Vimal, R.L.P., Császár, N., Aslani, M., Bókkon, I.* (2017) Phosphenes, retinal dark noise, negative afterimages and retinogeniculate projection:A review of a new explanatory framework based on endogenous ocular luminescence. Progress in Retinal and Eye Research. 60:101-119.
• Császár, N., Salari, V., Scholkmann, F., Kapócs, G., Bókkon, I.*(2016) The “hidden observer” as the cognitive unconscious during hypnosis. Activitas Nervosa Superior 58: 51-61.
• Kapócs, G, Scholkmann F, Salari V, Császár N, Szőke H, Bókkon I.*(2016) Possible role of biochemiluminescent photons for lysergic acid diethylamide (LSD)-induced phosphenes and visual hallucinations. Reviews in the Neurosciences 28:77-86.
• Salari V, Bókkon I, Ghobadia R, Scholkmann F, Tuszynskih JA. (2016) Relationship between intelligence and spectral characteristics of brain biophoton emission: Correlation does not automatically imply causation. PNAS 113(38):E5540
• Salari V, Scholkmann F, Shahbazi F, Bókkon I., Tuszynski JA. (2016) The Physical Mechanism for Retinal Discrete Dark Noise: Thermal Activation or Cellular Ultraweak Photon Emission? PloS One 11:e0148336
• Bókkon I*, Scholkmann F, Salari V, Császár-Nagy N, Kapócs G. (2016) Endogenous spontaneous ultra-weak photon emission in the formation of eye-specific retinogeniculate projections before birth. Reviews in the Neurosciences 27:411-419.
• Császár-Nagy N, Scholkmann F, Salari V, Szőke H, Bókkon I*. (2015) Phosphene perception is due to the ultra-weak photon emission produced in various parts of the visual system: glutamate in the focus. Reviews in the Neurosciences 27:291-299.
• Vimal R.L.P., Bókkon, I., Vas J. P., Császár, N. Szőke H. (2015) Transgenerational epigenetic mechanisms, unconscious creativity, and sensory deprivation: semi-Free Will in extended dual-aspect monism framework. Quantum Biosystems 6, 33-53
• Szőke H, Hegyi G. Császár, N. Vas J. P., Kapócs G. Bókkon, I*. (2015) Agyi képalkotás, mint vizuális alapú kognitív modell. A visual based proto-consciousness model of human thinking. Ideggyógyászati Szemle / Clinical Neuroscience 69(01-02)
• Mehta R, Singh A, Bókkon I., Mallick B.M. (2015) REM sleep and its loss-associated epigenetic regulation with reference to noradrenalin in particular. Curr Neuropharmacol. 14:28-40.
• Salari V., Scholkmann F., Shahbazi F., Dai J., Bokkon I., Tuszynski J.. (2015) Comment on “Activation of Visual Pigments by Light and Heat”[Science 332, 1307-312 (2011)] http://arxiv.org/abs/1501.06947
• Bókkon, I.*, Vas J. P., Császár, N. (2014) Gondolatok a szabad akaratról az epigenetika, a transzgenerációs trauma átvitel és a tudattalan folyamatok tükrében Magyar Pszichológiai Szemle, Hungarian Review of Psychology 69. 4/8. 797–819.
• Ashtari M, Cyckowski L, Yazdi A, Marshal K, Viands A, Bókkon I, Maguire A, Bennett J. (2014) ¬fMRI of Retinal Originated Phosphenes Experienced by Patients with Leber Congenital Amaurosis. PlOS One. 2014 Jan 21;9(1):e86068
• Bókkon, I.,* Vas J. P., Császár, N., Lukács, T. (2014) Challenges to free will: transgenerational epigenetic information, unconscious processes and vanishing twin syndrome. Reviews in the Neurosciences. 25(1):163-175.
• Bókkon I,* Mallick BN, Tuszynski JA. (2013) Near death experiences: A multidisciplinary hypothesis. Front. Hum. Neurosci. 7:533. doi: 10.3389/fnhum.2013.00533.
• Bókkon I,* Vimal RLP. (2013) Theoretical implications on (color) visual representation and cytochrome oxidase blobs. Activitas Nervosa Superior 55, 15-37 https://link.springer.com/content/pdf/10.1007/BF03379594.pdf
• Bókkon I*, Salari V, Scholkmann F, Dai J, Grass F. (2013) Interdisciplinary implications on autism, savantism, Asperger syndrome and the biophysical picture representation: Thinking in pictures. Cognitive Systems Research 22–23, 67–77.
• Bókkon I*, Mallick BN. (2012) Activation of retinotopic areas is central to REM sleep associated dreams: Visual dreams and visual imagery possibly co-emerged in evolution. Activitas Nervosa Superior 54,10-25 https://link.springer.com/content/pdf/10.1007/BF03379581.pdf
• Bókkon I, Vimal RLP. (2012) Subliminal afterimages via ocular delayed luminescence: transsaccade stability of the visual perception and color illusion. Activitas Nervosa Superior 54, 49-59.
• Bókkon I. (2012) Recognition of functional roles of free radicals. Curr Neuropharmacol. 10(4):287-288.
• Bókkon I*, Salari V. (2012) Brilliant lights by bioluminescent photons in near-death experiences. Medical Hypotheses 79, 47-49.
• Bókkon I*, Tuszynski J, Salari V. (2011) Biophysical visual virtual reality in retinotopic visual areas. European Biophysics Journal 40 (Suppl. 1) S67 Abstract.
• Salari V, Tuszynski J, Bókkon I, Rahnama M Cifra M. (2011) On the Photonic Cellular Interaction and the Electric Activity of Neurons in the Human Brain. Journal of Physics: Conference Series. 329 012006. (9th International Fröhlich’s Symposium, Electrodynamic Activity of Living Cells (EDALC11).
• Bókkon I*, Vimal RLP, Wang C, Dai J, Salari V, Grass F, Antal I. (2011) Visible light induced ocular delayed bioluminescence as a possible origin of negative afterimage. J. Photochem. Photobiol. B Biology. 103, 192–199.
• Rahnama M, Tuszynski J, Bókkon I, Cifra M, Sardar P, Salari V. (2011) Emission of mitochondrial biophotons and their effect on electrical activity of membrane via microtubules. J Integr Neurosci. 10, 65-88.
• Wang C, Bókkon I*, Dai J, Antal I. (2011) Spontaneous and visible light-induced ultra-weak photon emission from rat eyes. Brain Res. 1369. 1-9.
• Bókkon I*, Salari V, Tuszynski J. (2011) Emergence of intrinsic representations of images by feedforward and feedback processes and bioluminescent photons in early retinotopic areas (Toward biophysical homunculus by an iterative model). J Integr Neurosci. 10, 47-64.
• Bókkon I*, Antal I. (2011) Schizophrenia: redox regulation and volume transmission. Current Neuropharmacology 9, 289-300.
• Bókkon I*, Tuszynski J, Salari V. (2011) Biophysical visual virtual reality in retinotopic visual areas. Nature Precedings http://dx.doi.org/10.1038/npre.2011.6051.1
• Bókkon I*, Salari V, Tuszynski J, Antal I. (2010) Estimation of the number of biophotons involved in the visual perception of a single-object image: Biophoton intensity can be considerably higher inside cells than outside J. Photochem. Photobiol. B Biology 100, 160-166.
• Bókkon I*, Vimal RLP. (2010). Implications on visual apperception: energy, duration, structure and synchronization. BioSystems 101, 1-9.
• Bókkon I*, Dai J, Antal I. (2010) Picture representation during REM dreams: A redox molecular hypothesis. BioSystems. 100, 79-86.
• Banaclocha MA, Bókkon I, Banaclocha HM. (2010) Long-term memory in brain magnetite. Medical Hypotheses. 74, 254-257.
• Bókkon I*, Salari V. (2010) Information storing by biomagnetites. Journal of Biological Physics. 36, 109-120.
• Bókkon I*, Vimal RLP. (2009) Retinal phosphenes and discrete dark noises in rods: a new biophysical framework. J. Photochem. Photobiol. B Biology. 96, 255-259.
• Bókkon I. (2009) Visual perception and imagery: a new hypothesis. BioSystems 96, 178-184.
• Bókkon I*, Kirby M, D’Angiulli A. (2009) TMS, phosphenes and visual mental imagery: A mini-review and a theoretical framework. Nature Precedings http://dx.doi.org/10.1038/npre.2009.3244.1
• Bókkon I*, D'Angiulli A. (2009) Emergence and transmission of visual awareness through optical coding in the brain: A redox molecular hypothesis on visual mental imagery. Bioscience Hypotheses 2, 226-232.
• Bókkon I. (2008) Phosphene phenomenon: a new concept. BioSystems 92, 168-174.
• Bókkon I. (2006) Dream pictures, neuroholography and the laws of physics. Journal of Sleep Research. Vol. 15, Supplement I. Abstract. p:187.
• Bókkon I. (2005) Dreams and Neuroholography: An interdisciplinary interpretation of development of homeotherm state in evolution. Sleep and Hypnosis 7, 61-76.
• Bókkon I. (2007) A víz több, mint pusztán H2O. (Water is more than just H2O)
• Biokémia Quarterly Bulletin of Hungarian Biochemical Society Jun.22-27.
• Bókkon I. Balogh I. Kocsis Zs. (2009) Functional anaerobic processes in aerobic eukaryote cells in connection with nickel. Unpublished
• Bókkon I*, Balogh I., Kocsis Zs. (2006) Nickel: Toxic versus essential. (Eds: Szilágyi M. Szentmihályi K.) In Proceedings of International Symposium on Trace Elements in the Food Chain (TEFC) Budapest, Hungary, 2006 pp.524-529.
• Bókkon I. (2005) Biomágnesek, mint információtárolók. (Biomagnetites as information storages) Biokémia Quarterly Bulletin of Hungarian Biochemical Society Sep. 32-36.
• Bókkon I. (2003) Creative Information. Journal of Biological Systems. 1, 1-17.
• Bókkon I. (2002) A nanobaktériumok világa (The world of nanobacterie). Biokémia. Quarterly Bulletin of Hungarian Biochemical Society Jun. 26, 35-42.
• Bókkon I. (2002) Budapesti Műszaki és Közgazdaságtudományi Egyetem, Mezőgazdasági Tanszék, Dr. Janzsó Béla Mikrobiológiai Jegyzet. Nanobaktériumok fejezet (Nanobacterie part in Budapest University of Technology, note-book for students).
• Bókkon I. (2000) Tudatos és tudatalatti információtárolás az agyban. (Conscious and unconscious information storage in the brain). Biokémia. Quarterly Bulletin of Hungarian Biochemical Society. Sep. 24, 79-83.
EMOST papers
• Bókkon I, Erdöfi-Szabó A, Till A, Lukács T, Erdöfi-Szabó É. (2013) EMOST: Elimination of chronic constipation and persistent diarrhoea by low-frequency and intensity electromagnetic treatment in children: case reports. Electromagnetic Biology and Medicine 2013 Jun 19.
• Bókkon I, Erdöfi-Szabó A, Till A, Balázs R, Sárosi Z, Szabó ZL, Kolonics G, Popper G, (2012) EMOST: Report about the application of low-frequency and intensity electromagnetic fields in disaster situation and commando training. Electromagnetic Biology and Medicine 31, 394-403.
• Bókkon I, Till A, Erdıfi-Szabo A. (2011) Non-ionizing electro-magnetic-own-signal-treatment. European Biophysical Journal. 40 (Suppl. 1):S191 Abstract.
• Bókkon I, Till A, Grass F, Erdöfi-Szabó A (2011) Phantom pain reduction by electromagnetic treatment. Electromagnetic Biology and Medicine 30, 115-127.
Posters
• Bókkon I, Tuszynski J, Salari V. (2011) Biophysical visual virtual reality in retinotopic visual areas. 8th European Biophysics Congress. 23-27 August, Budapest, Hungary.
• Bókkon I, Till A, Erdöfi-Szabó A (2011) Non-ionizing Electromagnetic-Own-Signal-Treatment. 8th European Biophysics Congress. 23-27 August, Budapest, Hungary.
• Rahnama M, Bókkon I, Tuszynski J, Cifra M, Sardar P, Salari V. (2011) Investigation Of Biophotons Emissions, Microtubule Activity And Action Potentials In The Human Brain. Toward a Science of Consciousness Conference 2011, Stockholm, Sweden (May 2-8, 2011).
• Salari V, Tuszynski J, Bókkon I, Cifra M. (2011) On the Photonic Cellular Communication/Interaction and the Electric Activity of Neurons in the Human Brain. Electrodynamic activity of living cells, 9th International Fröhlich’s Symposium. Including Microtubule Coherent Modes and Cancer Cell Physics, July 1-3, 2011 Prague.
• Bókkon I, Till A, Erdöfi-Szabó A (2010) Phantom Pain Reduction by Non-ionizing Electromagnetic Treatment. International Conference of Preventive Medicine and Public Health. 19-20 Nov. Pécs, Hungary.
• Bókkon I, D’Angiulli A. (2009) The biophysics of TMS-induced state-dependent phosphenes: A molecular mechanism for the visual buffer? [Abstract]. In N.A. Taatgen & H. van Rijn (Eds.), Proceedings of the 31th Annual Conference of the Cognitive Science Society (p. NUMBER). Cognitive Science Society. Amsterdam, July 29-Aug 1, 2009, VU University Amsterdam. http://csjarchive.cogsci.rpi.edu/proceedings/2009/papers/690/index.html
• Rahnama M., Bókkon I., Salari V., Sardar P. (2009) Biophotons Emission and EEG Diagrams: A Computational Approach. Toward a Science of Consciousness Conference, from June 11th to 14th, .2009 Hong Kong.
• Bókkon I., Kyrby M., D’Angiulli A. (2008) TMS, phosphenes and visual mental imagery: A mini-review and a theoretical framework. 1st North American Symposium on TMS and Neuroimaging in Cognition and Behaviour Montréal (Canada) 25-26 September 2008.
• Bókkon I. (2006) Dream pictures, neuroholography and the laws of physics. 18th Congress of the European Sleep Research Society, Innsbruck.
• Bókkon I., Balogh I., Kocsis Zs. (2006) Nickel: toxic versus essential. International Symposium on Trace Elements in the Food Chain Budapest, Hungary, 2006. May 25-27.
• Bókkon I. (2001) Nanobaktériumok (Nanobacteries). IX. Sejt- és Fejlődésbiológiai Napok, Hungary, Debrecen. IX. Cell- and Evolutionary Biology Days, Debrecen.
• Bókkon I. Gonda Zs. (2001) Endotoxinok és korszerű mennyiségi meghatározásuk. OKK-OKBI. VIII. Primer Prevenciós Fórum, Budapest. Endotoxins and modern assay of them. VIII. Primer Prevention Forum. National Institute of Chemical Safety.
• Bókkon I. (1999) Kristálytudat (Crystal Consciousness). A Természetes környezet, Az ember és kölcsönhatásaik. III. Országos Konferencia. The natural environment, The man and their interactions III. Nationwide Conference.
Performances
• Bókkon I. (2009) Molecular bases of biophysical picture representation in retinotopic V1/V2 areas. Peter Pazmany Catholic University, Faculty of Information Technology.
• Bókkon I. (2003) Neuroholográfia (Neuoroholography): Álom és tudat a neuroholgráfia tükrében. Dream and consciousness of the mirror of neuroholography. Semmelweis University, Department of Behavioural Sciences.
• Bókkon I. (2001) A kreatív információ (Creative Information). A Természetes környezet, Az ember és kölcsönhatásaik. IV. Országos Konferencia. The natural environment, The man and their interactions IV. Nationwide Conference.
• Bókkon I. (2000) Biokristályok és biomágnesek (Biocrystals and biomagnatites). Semmelweis University, Genetikai- Sejt- és Immunológiai Intézet. Department of Genetics, Cell and Immunobiology.
• Bókkon I. (1995) A gyenge elektromos, mágneses és elektromágneses sugárzások biokémiai hatásai. (Biochemical effects of weak electric, magnetic and electromagnetic radiation) BME, Budapest University of Technology.